The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 08, 2022

Filed:

Dec. 30, 2021
Applicants:

New York University, New York, NY (US);

Argenx Iip Bv, Ghent, BE;

Inventors:

Steven J. Burden, New York, NY (US);

Shohei Koide, New York, NY (US);

Akiko Koide, New York, NY (US);

Nadia Leloup, New York, NY (US);

Julien Oury, New York, NY (US);

Karen Silence, Ghent, BE;

Roeland Vanhauwaert, Ghent, BE;

Christophe Blanchetot, Ghent, BE;

Assignees:

NEW YORK UNIVERSITY, New York, NY (US);

ARGENX IIP BV, Ghent, BE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C07K 16/28 (2006.01); A61P 21/04 (2006.01);
U.S. Cl.
CPC ...
C07K 16/28 (2013.01); A61P 21/04 (2018.01); C07K 2317/21 (2013.01); C07K 2317/55 (2013.01); C07K 2317/622 (2013.01);
Abstract

The present invention relates to antibody-based molecules, including full-length antibodies, antigen-binding domains thereof, and antibody derivatives that are capable of binding to and activating human muscle-specific tyrosine protein kinase (MuSK). The present invention further discloses methods of treating neuromuscular conditions using the aforementioned MuSK antibodies.


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