The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 2022
Filed:
Sep. 16, 2019
Applicant:
Gi Innovation, Inc., Seoul, KR;
Inventor:
Myung Ho Jang, Seoul, KR;
Assignee:
GI INNOVATION, INC., Seoul, KR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/55 (2006.01); A61P 31/12 (2006.01); A61P 35/00 (2006.01); C07K 14/705 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/55 (2013.01); A61P 31/12 (2018.01); A61P 35/00 (2018.01); C07K 14/70532 (2013.01); A61K 38/00 (2013.01); C07K 2319/31 (2013.01);
Abstract
Provided is a fusion protein comprising IL-2 protein and CD80 protein. A fusion protein comprising CD80 fragment, immunoglobulin Fe, and an IL-2 variant can activate immune cells, such as natural killer cells, and at the same time, can control immune cell regulatory activity of regulatory T cells. Therefore, a pharmaceutical composition comprising the fusion protein as an active ingredient is very industrially useful in that such pharmaceutical composition can increase immune activity in the body, and thus can be effectively used against infectious diseases as well as cancer.