The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 2022
Filed:
Sep. 11, 2020
Mirati Therapeutics, Inc., San Diego, CA (US);
Thomas P. Bobinski, San Diego, CA (US);
Christopher Ronald Smith, San Diego, CA (US);
Matthew Arnold Marx, San Diego, CA (US);
John Michael Ketcham, San Diego, CA (US);
Aaron Craig Burns, San Diego, CA (US);
John David Lawson, Carlsbad, CA (US);
Svitlana Kulyk, Redwood City, CA (US);
Jon Kuehler, San Diego, CA (US);
Anthony Ivetac, San Diego, CA (US);
Mirati Therapeutics, Inc., San Diego, CA (US);
Abstract
The present invention relates to compounds that inhibit Protein Arginine N-Methyl Transferase 5 (PRMT5) activity. In particular, the present invention relates to compounds of Formula (I) to pharmaceutical compositions comprising compounds of Formula (I) and to methods of use thereof, such as methods of treating cancer using the compounds of Formula (I) and pharmaceutical compositions comprising those compounds.