The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 2022
Filed:
May. 31, 2017
Applicant:
Human Biomolecular Research Institute, San Diego, CA (US);
Inventors:
John R Cashman, San Diego, CA (US);
Daniel J Ryan, El Segundo, CA (US);
Karl Okolotowicz, Omaha, NE (US);
Assignee:
Human Biomolecular Research Institute, San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 213/02 (2006.01); C07C 217/58 (2006.01); A61P 9/06 (2006.01); A61P 25/08 (2006.01); C07D 213/64 (2006.01); C07D 213/65 (2006.01); C07D 213/68 (2006.01); A61K 35/12 (2015.01); A61K 31/138 (2006.01); A61K 31/44 (2006.01); A61K 35/545 (2015.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07C 217/58 (2013.01); A61K 31/138 (2013.01); A61K 31/44 (2013.01); A61K 35/12 (2013.01); A61K 35/545 (2013.01); A61P 9/06 (2018.01); A61P 25/08 (2018.01); C07D 213/64 (2013.01); C07D 213/65 (2013.01); C07D 213/68 (2013.01); A61K 45/06 (2013.01);
Abstract
Methods and small molecule compounds for inhibition of sodium channels are provided. One example of a class of compounds that may be used is represented by the compound of Formula (I) or a pharmaceutically acceptable salt, N-oxide or solvate thereof, wherein A, B, D, R, R, R', R, R, R, R, R, R, Rare as described herein.