The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 08, 2022

Filed:

Aug. 11, 2021
Applicant:

Alpheus Medical, Inc., Oakdale, MN (US);

Inventors:

Vijay Agarwal, New York, NY (US);

Braden Eliason, Minneapolis, MN (US);

Jeremy Ling, Mendota Heights, MN (US);

Assignee:

Alpheus Medical, Inc., Oakdale, MN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61N 7/00 (2006.01); A61K 9/00 (2006.01); A61K 31/197 (2006.01); A61K 41/00 (2020.01); B06B 1/02 (2006.01); B06B 1/06 (2006.01); A61P 35/00 (2006.01); A61F 7/00 (2006.01); A61B 17/00 (2006.01); A61B 18/00 (2006.01); A61F 7/02 (2006.01); A61B 17/32 (2006.01);
U.S. Cl.
CPC ...
A61N 7/00 (2013.01); A61F 7/0085 (2013.01); A61K 9/0053 (2013.01); A61K 31/197 (2013.01); A61K 41/0033 (2013.01); A61K 41/0061 (2013.01); A61P 35/00 (2018.01); B06B 1/0207 (2013.01); B06B 1/0622 (2013.01); A61B 2017/00084 (2013.01); A61B 2017/320069 (2017.08); A61B 2018/00023 (2013.01); A61B 2018/00446 (2013.01); A61F 2007/0056 (2013.01); A61F 2007/0096 (2013.01); A61F 2007/0288 (2013.01); A61N 2007/003 (2013.01); A61N 2007/006 (2013.01); A61N 2007/0073 (2013.01); A61N 2007/0078 (2013.01); A61N 2007/0082 (2013.01); A61N 2007/0095 (2013.01); B06B 2201/76 (2013.01);
Abstract

Disclosed are methods of obtaining zero vergence ultrasound waves for providing sonodynamic therapy with ultrasound waves that do not converge and do not diverge. The method includes coupling a sonodynamic therapy device with an array of flat piezoelectric transducers to a skin surface. A controller is configured to generate an electrical drive signal at a frequency, modulate the drive signal, and drive the transducer with the modulated drive signal at the frequency to produce a zero vergence ultrasound wave to produce an average acoustic intensity sufficient to activate a sonosensitizer in a treatment region without damaging healthy cells in the treatment region.


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