The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 2022
Filed:
Sep. 26, 2019
Siemens Healthcare Gmbh, Erlangen, DE;
The Cleveland Clinic Foundation, Cleveland, OH (US);
Bin Lou, Princeton, NJ (US);
Ali Kamen, Skillman, NJ (US);
Nilesh Mistry, Erlangen, DE;
Lance Anthony Ladic, Robbinsville, NJ (US);
Mohamed Abazeed, Cleveland, OH (US);
Siemens Healthcare GmbH, Erlangen, DE;
The Cleveland Clinic Foundation, Cleveland, OH (US);
Abstract
For decision support in a medical therapy, machine learning provides a machine-learned generator for generating a prediction of outcome for therapy personalized to a patient. The outcome prediction may be used to determine dose. To assist in decision support, a regression analysis of the cohort used for machine training relates the outcome from the machine-learned generator to the dose and an actual control time (e.g., time-to-event). The dose that minimizes side effects while minimizing risk of failure to a time for any given patient is determined from the outcome for that patient and a calibration from the regression analysis.