The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 2022
Filed:
Mar. 29, 2022
Applicant:
The Rockefeller University, New York, NY (US);
Inventors:
David Bikard, Paris, FR;
Luciano Marraffini, Brooklyn, NY (US);
Assignee:
The Rockefeller University, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/46 (2006.01); C12N 9/16 (2006.01); A61K 45/06 (2006.01); A61K 31/7105 (2006.01); C12N 15/113 (2010.01); A61K 31/713 (2006.01); A01N 63/00 (2020.01); C12N 9/22 (2006.01); C12N 15/74 (2006.01);
U.S. Cl.
CPC ...
A61K 38/465 (2013.01); A01N 63/00 (2013.01); A61K 31/713 (2013.01); A61K 31/7105 (2013.01); A61K 45/06 (2013.01); C12N 9/16 (2013.01); C12N 9/22 (2013.01); C12N 15/113 (2013.01); C12N 15/74 (2013.01); C12Y 301/00 (2013.01); C12N 2310/10 (2013.01); C12N 2310/20 (2017.05); C12N 2795/10331 (2013.01); C12N 2795/10332 (2013.01); C12N 2795/10343 (2013.01); C12N 2795/10371 (2013.01);
Abstract
Provided are compositions and methods for selectively reducing the amount of antibiotic resistant and/or virulent bacteria in a mixed bacteria population, or for reducing any other type of unwanted bacteria in a mixed bacteria population. The compositions and methods involve targeting bacteria that are differentiated from other members of the population by at least one unique clustered regularly interspaced short palindromic repeats (CRISPR) targeted DNA sequence. The compositions and methods can be readily adapted to target any bacteria or any bacteria plasmid, or both.