The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 2022
Filed:
Sep. 25, 2020
Gflas Life Sciences, Inc., Seoul, KR;
Seoul National University R&db Foundation, Seoul, KR;
Sungyong In, Germantown, MD (US);
Sunghwa Choe, Seoul, KR;
Mi Jin Park, Seoul, KR;
Aiden Y. Park, Seoul, KR;
Jung Hak Lim, Seoul, KR;
Dong Wook Kim, Seoul, KR;
Youngdong Yoo, Seoul, KR;
Jongjin Park, West Lafayette, IN (US);
GFLAS LIFE SCIENCES, INC., Seoul, KR;
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION, Seoul, KR;
Abstract
Enhanced, specific nucleic acid targeting complexes comprising endo and exonuclease activity, and related methods that allow both targeted degradation of specific and/or non-specific nucleic acids in vivo and specific temporal regulation of nuclease activity to prevent off-target activity are disclosed herein. Through practice of the disclosure, nucleic acids, and cells harboring them, such as cancer cells or pathogens, are selectively degraded in vivo.