The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 2022
Filed:
Sep. 24, 2019
Applicant:
Verona Pharma Plc, Cardiff, GB;
Inventors:
Peter Lionel Spargo, Canterbury, GB;
Edward James French, Canterbury, GB;
Julian Scott Northen, South Shields, GB;
John Mykytiuk, Houghton-le-Spring, GB;
Assignee:
VERONA PHARMA PLC, Cardiff, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/513 (2006.01); C07D 471/04 (2006.01); A61K 9/00 (2006.01); A61K 31/185 (2006.01); A61K 31/519 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/513 (2013.01); A61K 9/0075 (2013.01); A61K 31/185 (2013.01); A61K 31/519 (2013.01); A61K 45/06 (2013.01); C07D 471/04 (2013.01); A61K 2300/00 (2013.01);
Abstract
The present invention relates to a pharmaceutically acceptable acid addition salt of: (i) 9,10-dimethoxy-2-(2,4,6-tri-methylphenylimino)-3-(N-carbamoyl-2-aminoethyl)-3,4,6,7-tetrahydro-2H-pyrimido[6,1-a]isoquinolin-4-one (RPL554); and (ii) ethane-1,2-disulfonic acid, ethanesulfonic acid, methanesulfonic acid, benzenesulfonic acid, p-toluenesulfonic acid, hydrochloric acid, hydrobromic acid, phosphoric acid or sulfuric acid.