The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 2022
Filed:
Feb. 13, 2018
Applicant:
Research Triangle Institute, Research Triangle Park, NC (US);
Inventors:
Yanan Zhang, Apex, NC (US);
Thuy Nguyen, Morrisville, NC (US);
Assignee:
RESEARCH TRIANGLE INSTITUTE, Research Triangle Park, NC (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/401 (2006.01); A61P 25/04 (2006.01); A61P 25/36 (2006.01); A61K 31/40 (2006.01); A61P 25/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/40 (2013.01); A61P 25/00 (2018.01);
Abstract
Neuropeptide FF receptor modulators based on a proline scaffold are provided which offer NPFF receptor potencies in the nanomolar range and antagonistic selectivity for the NPFF1 receptor. Methods, compounds and compositions for modulating the function of neuropeptide FF receptors are provided for pharmacotherapies capable of influencing conditions or disorders affected by the neuropeptide FF receptors.