The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 08, 2022

Filed:

Jul. 08, 2016
Applicant:

The Board of Regents of the University of Texas System, Austin, TX (US);

Inventors:

Connie Hsia, Dallas, TX (US);

Yi Hong, Irving, TX (US);

Orson W. Moe, Dallas, TX (US);

Kytai Nguyen, Grand Prairie, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 9/00 (2006.01); A61P 11/00 (2006.01); A61K 31/713 (2006.01); A61K 38/47 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5176 (2013.01); A61K 9/0019 (2013.01); A61K 9/0078 (2013.01); A61K 9/5153 (2013.01); A61K 31/713 (2013.01); A61K 38/47 (2013.01); A61P 11/00 (2018.01); C12Y 302/01031 (2013.01);
Abstract

Nanoparticles coated with extracellular matrix (ECM) are provided, in some aspects, for the delivery of a therapeutic protein, nucleic acid, or drug. In some embodiments, the nanoparticles are delivered to a subject via inhalation or aerosol delivery. Also provided, in some aspects, are methods for treating acute lung injury comprising administering α-Klotho (αKlotho) protein or DNA to a subject.


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