logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11485984 B1

PDFFull Text
Date of Patent:
Nov. 01, 2022

Filed:

May. 23, 2012

Method for introducing hepatocyte growth factor and neurogenin 1 into mesenchymal stem cells

Applicants:

Hae Young Suh, Gyeonggi-do, KR;

Sung Soo Kim, Seoul, KR;

Seung Wan Yoo, Seoul, KR;

Young Don Lee, Gyeonggi-do, KR;

Inventors:

Hae Young Suh, Gyeonggi-do, KR;

Sung Soo Kim, Seoul, KR;

Seung Wan Yoo, Seoul, KR;

Young Don Lee, Gyeonggi-do, KR;

Assignee:

CELL & BRAIN CO., LTD, Jeollabuk-do, KR;

Attorney:

Workman Nydegger

Primary Examiner:

Anoop K Singh

Assistant Examiner:

Magdalene K Sgagias

Int. Cl.
CPC ...
C12N 15/85 (2006.01); A61K 35/28 (2015.01); A61K 35/30 (2015.01); C12N 5/0775 (2010.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
C12N 15/85 (2013.01); A61K 35/28 (2013.01); A61K 35/30 (2013.01); C12N 5/0663 (2013.01); C12N 15/86 (2013.01); C12N 2501/12 (2013.01); C12N 2501/60 (2013.01); C12N 2510/00 (2013.01);
Abstract

The present invention relates to an adult stem cell line introduced with an HGF gene and a neurogenic transcription factor gene of a bHLH family, a preparation method of the adult stem cell line, a composition for the prevention or treatment of neurological diseases comprising the adult stem cell line, and a method for treating neurological diseases comprising the step of administering the composition to a subject having neurological diseases or suspected of having neurological diseases. The adult stem cells according to the present invention, which are introduced with an HGF gene and a neurogenic transcription factor gene of a bHLH family, can be used to overcome chronic impairment caused by cell death following stroke. Thus, the adult stem cells can be developed as a novel therapeutic agent or widely used in clinical trial and research for cell replacement therapy and gene therapy that are applicable to neurological diseases including Parkinson's disease, Alzheimer disease, and spinal cord injury as well as stroke.

Find Patent Forward Citations

Quick Actions:

Suh, Hae. (2022). Method for introducing hepatocyte growth factor and neurogenin 1 into mesenchymal stem cells (U.S. Patent No. 11485984). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11485984

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…