The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 01, 2022

Filed:

Dec. 19, 2014
Applicant:

Adagene Inc., Cayman Islands, GB;

Inventors:

Fangyong Du, New Haven, CT (US);

Peter Peizhi Luo, Lansdale, PA (US);

Assignee:

ADAGENE, INC., Grand Cayman, KY;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/63 (2006.01); C07K 16/06 (2006.01); C12N 15/72 (2006.01); C12N 15/73 (2006.01);
U.S. Cl.
CPC ...
C12N 15/635 (2013.01); C07K 16/06 (2013.01); C12N 15/63 (2013.01); C12N 15/72 (2013.01); C12N 15/73 (2013.01); C07K 2317/14 (2013.01); C07K 2317/55 (2013.01);
Abstract

Methods and systems for autoinduction of gene expression, without the need to add exogenous inducers. A dual genetic element system, which includes a first, high copy number genetic element comprising a first gene of interest that is under the control of an inducible promoter, and a second, low copy number genetic element comprising a gene encoding a transcriptional factor which, upon expression, regulates transcription from the inducible promoter, wherein activation of transcription from the inducible promoter does not require addition of an exogenous inducer.


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