The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 01, 2022
Filed:
Oct. 11, 2017
Mgi Tech Co., Ltd., Shenzhen, CN;
Complete Genomics, Inc., San Jose, CA (US);
Hui Wang, Shenzhen, CN;
Xun Xu, Shenzhen, CN;
Jin Yang, Shenzhen, CN;
Ao Chen, Shenzhen, CN;
Chongjun Xu, San Jose, CA (US);
Wenwei Zhang, Shenzhen, CN;
MGI TECH CO., LTD., Guangdong, CN;
COMPLETE GENOMICS, INC., San Jose, CA (US);
Abstract
The present invention provides a method for improving the loading of nucleic acid on a solid support by contacting the solid support with a poloxamer-containing reagent. The present invention also provides a method for improving the stability of a nucleic acid on a solid support, comprising contacting a nucleic acid molecule with a partially double-strand oligonucleotide before or after loading the nucleic acid molecule on a solid support, so as to cause the nucleic acid molecule to hybridize with the oligonucleotide. The present invention also provides a combined use of the two methods.