The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 01, 2022

Filed:

Oct. 07, 2020
Applicant:

Novartis Ag, Basel, CH;

Inventors:

Amy Calhoun, Cambridge, MA (US);

Xin Chen, Lexington, MA (US);

Kevin Matthew Gardinier, Arlington, MA (US);

Edward Charles Hall, Boston, MA (US);

Keith Jendza, Boston, MA (US);

Nancy Labbe-Giguere, Arlington, MA (US);

James Neef, Stow, MA (US);

Daniel Steven Palacios, Cambridge, MA (US);

Ming Qian, Watertown, MA (US);

Michael David Shultz, Lexington, MA (US);

Christopher G. Thomson, Herts, GB;

Kate Yaping Wang, Boxborough, MA (US);

Fan Yang, West Roxbury, MA (US);

Assignee:

NOVARTIS AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/107 (2006.01); A61P 25/18 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 491/107 (2013.01); A61K 45/06 (2013.01); A61P 25/18 (2018.01);
Abstract

Provided herein are compounds according to Formula (I) or a pharmaceutically acceptable salt thereof, wherein R, R, R, R, and Rare defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) as well as the use of such compounds as M4 receptor agonists.


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