The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 01, 2022

Filed:

Feb. 13, 2019
Applicants:

Boehringer Ingelheim International Gmbh, Ingelheim am Rhein, DE;

Hydra Biosciences, Llc, Belmont, MA (US);

Inventors:

Steven Brunette, Ridgefield, CT (US);

Jianwen Cui, Ridgefield, CT (US);

Michael D. Lowe, Pleasantville, NY (US);

Christopher Ronald Sarko, San Ramon, CA (US);

Simon Surprenant, Boisbriand, CA;

Michael Robert Turner, Danbury, CT (US);

Xinyuan Wu, Newton, MA (US);

Lana Louise Smith Keenan, Poughquag, NY (US);

Thierry Bouyssou, Ingelheim am Rhein, DE;

Paul Nicklin, Ingelheim am Rhein, DE;

Assignees:

Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;

Hydra Biosciences, LLC, Belmont, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/08 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01);
U.S. Cl.
CPC ...
C07D 487/08 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01);
Abstract

The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts therefore, wherein Rto R, A, U, V, W, X, Y, and Z are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.


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