The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 01, 2022

Filed:

Mar. 16, 2018
Applicant:

Argonaut Therapeutics Limited, Oxford, GB;

Inventors:

Andrew Morley, Cambridge, GB;

Rebecca Miller, Oxford, GB;

Nicholas La Thangue, Oxford, GB;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/14 (2006.01); A61P 35/00 (2006.01); C07D 401/12 (2006.01); C07D 409/14 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 495/04 (2006.01); C07D 498/08 (2006.01);
U.S. Cl.
CPC ...
C07D 413/14 (2013.01); A61P 35/00 (2018.01); C07D 401/12 (2013.01); C07D 409/14 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07D 495/04 (2013.01); C07D 498/08 (2013.01);
Abstract

The present disclosure relates to compounds suitable for the inhibition of protein arginine methyl-transferase (PRMT), in particular PRMT5. These compounds may be for use as therapeutic agents, in particular, agents for use in the treatment and/or prevention of proliferative diseases, such as cancer.


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