The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 01, 2022

Filed:

Nov. 14, 2018
Applicant:

Auransa Inc., Palo Alto, CA (US);

Inventors:

Andrew Asher Protter, Palo Alto, CA (US);

Michael John Green, Half Moon Bay, CA (US);

Hak Jin Chang, Harvard, MA (US);

Son Minh Pham, San Francisco, CA (US);

Sarvajit Chakravarty, Edmond, OK (US);

Gregory R. Luedtke, Salinas, CA (US);

Pek Yee Lum, Palo Alto, CA (US);

Assignee:

Auransa Inc., Palo Alto, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/06 (2006.01); C07D 401/14 (2006.01); C07D 211/86 (2006.01); C07D 211/96 (2006.01); C07D 413/06 (2006.01); C07D 491/056 (2006.01); C07D 405/06 (2006.01); C07D 405/14 (2006.01); C07D 401/12 (2006.01); C07D 401/04 (2006.01); C07D 403/06 (2006.01); C07D 223/10 (2006.01);
U.S. Cl.
CPC ...
C07D 401/06 (2013.01); C07D 211/86 (2013.01); C07D 211/96 (2013.01); C07D 223/10 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/06 (2013.01); C07D 405/06 (2013.01); C07D 405/14 (2013.01); C07D 413/06 (2013.01); C07D 491/056 (2013.01);
Abstract

The present invention relates to a group of 1-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]-2,3-dihydropyridin-6-one (piperlongumine) derivatives, analogs and pharmaceutically acceptable salts thereof. The present invention also relates to processes for preparing the same; a pharmaceutical composition and formulation containing a derivative of piperlongumine; and use of the derivatives and analogs for treating cancer.


Find Patent Forward Citations

Loading…