The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 01, 2022

Filed:

May. 24, 2019
Applicants:

Essa Pharma, Inc., Vancouver, CA;

The University of British Columbia, Vancouver, CA;

Provincial Health Services Authority, Vancouver, CA;

Inventors:

Han-Jie Zhou, Foster City, CA (US);

Peter Virsik, Portola Valley, CA (US);

Raymond John Andersen, Vancouver, CA;

Marianne Dorothy Sadar, West Vancouver, CA;

Kunzhong Jian, Surrey, CA;

Daniel Andrew Golec, Vancouver, CA;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/34 (2006.01); A61K 45/06 (2006.01); C07C 69/712 (2006.01); C07C 235/74 (2006.01); C07C 317/24 (2006.01); C07C 317/28 (2006.01); C07D 207/24 (2006.01); C07D 263/56 (2006.01); C07D 295/26 (2006.01); C07D 305/06 (2006.01);
U.S. Cl.
CPC ...
C07D 239/34 (2013.01); A61K 45/06 (2013.01); C07C 69/712 (2013.01); C07C 235/74 (2013.01); C07C 317/24 (2013.01); C07C 317/28 (2013.01); C07D 207/24 (2013.01); C07D 263/56 (2013.01); C07D 295/26 (2013.01); C07D 305/06 (2013.01);
Abstract

Compounds having a structure of formula (I), (I-A), (Ia)-(Ie), (A)-(E), and (II) or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof are provided. Uses of such compounds for modulating androgen receptor activity, imaging diagnostics in cancer and therapeutics, and methods for treatment of disorders including prostate cancer are also provided.


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