The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 01, 2022
Filed:
Nov. 08, 2018
Alfred E. Mann Institute for Biomedical Engineering AT the University of Southern California, Los Angeles, CA (US);
Yang Chai, Pasadena, CA (US);
Yong Chen, La Canada, CA (US);
Yuan Yuan, Los Angeles, CA (US);
Yuxing Guo, Los Angeles, CA (US);
Xiangjia Li, Los Angeles, CA (US);
Zoe Johnson, Los Angeles, CA (US);
ALFRED E. MANN INSTITUTE FOR BIOMEDICAL ENGINEERING AT THE UNIVERSITY OF SOUTHERN CALIFORNIA, Los Angeles, CA (US);
Abstract
This invention relates to a bone regeneration product comprising at least one stem cell, at least one scaffold, and at least one stem cell. The stem cells suitable for this invention may comprise stem cells suitable for a dense bone regeneration, stem cells suitable for a spongy bone regeneration, or a combination thereof. The bone regeneration product may further comprise a growth factor. This invention also relates to a bone regeneration method and treatment of any bone that has a critical size defect. This invention also relates to a scaffold. This invention further relates to a 3D printed scaffold comprising hydroxyapatite (HA) and tricalcium phosphate (TCP). This invention also relates to a scaffold comprising a polymer. The polymer of this invention may be prepared by using photocurable polymers and/or monomers. The scaffold of this invention may comprise a growth factor and a small molecule. The small molecule N may be a Smurf1 inhibitor.