The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 01, 2022

Filed:

Dec. 19, 2019
Applicants:

Cedars-sinai Medical Center, Los Angeles, CA (US);

Warsaw Orthopedic, Inc., Warsaw, IN (US);

Inventors:

Juliane Glaeser, Los Angeles, CA (US);

Hyun Bae, Los Angeles, CA (US);

Linda Kanim, Los Angeles, CA (US);

Dmitriy Sheyn, Los Angeles, CA (US);

Khosrowdad Salehi, Los Angeles, CA (US);

Assignees:

Cedars-Sinai Medical Center, Los Angeles, CA (US);

Warsaw Orthopedic, Inc., Warsaw, IN (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); A61K 38/08 (2019.01); A61K 38/17 (2006.01); A61P 29/00 (2006.01); A61K 9/00 (2006.01); A61K 47/42 (2017.01);
U.S. Cl.
CPC ...
A61K 38/1875 (2013.01); A61K 9/0085 (2013.01); A61K 38/08 (2013.01); A61K 38/1709 (2013.01); A61K 47/42 (2013.01); A61P 29/00 (2018.01);
Abstract

An osteogenic composition for implantation at or near a target tissue site beneath the skin is provided, the osteogenic composition comprising bone morphogenetic protein and a NEMO binding domain peptide, where the NEMO binding domain peptide reduces soft tissue inflammation at or near the target tissue site. In some embodiments, a method is provided for treating a target tissue site in a patient in need of such treatment, the method comprising implanting an osteogenic composition comprising bone morphogenetic protein and a NEMO binding domain peptide, where the NEMO binding domain peptide reduces soft tissue inflammation at or near the target tissue site.


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