The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 25, 2022
Filed:
Oct. 21, 2016
Applicant:
Novartis Ag, Basel, CH;
Inventors:
Naveen Dakappagari, Carlsbad, CA (US);
Jennifer Bordeaux, Carlsbad, CA (US);
Thai Tran, Carlsbad, CA (US);
Ju Young Kim, Carlsbad, CA (US);
Assignee:
NOVARTIS AG, Basel, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/569 (2006.01); G01N 33/574 (2006.01); G01N 21/64 (2006.01); C12Q 1/6886 (2018.01); C12Q 1/6841 (2018.01);
U.S. Cl.
CPC ...
G01N 33/56972 (2013.01); C12Q 1/6841 (2013.01); C12Q 1/6886 (2013.01); G01N 21/6428 (2013.01); G01N 33/56966 (2013.01); G01N 33/574 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/158 (2013.01); G01N 2800/52 (2013.01);
Abstract
The invention relates, in part, to methods of deriving a value for % biomarker positivity (PBP) for all cells or optionally, one or more subsets thereof, present in a field of view of a tissue sample from a cancer patient. The values for PBP can be indicative of a patient's response to immunotherapy.