The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 25, 2022
Filed:
May. 10, 2016
Natera, Inc., San Carlos, CA (US);
Huseyin Eser Kirkizlar, Los Angeles, CA (US);
Raheleh Salari, San Carlos, CA (US);
Styrmir Sigurjonsson, San Jose, CA (US);
Bernhard Zimmermann, Manteca, CA (US);
Allison Ryan, Belmont, CA (US);
Naresh Vankayalapati, San Francisco, CA (US);
Natera, Inc., San Carlos, CA (US);
Abstract
The invention provides improved methods, compositions, and kits for detecting ploidy of chromosome regions, e.g. for detecting cancer or a chromosomal abnormality in a gestating fetus. The methods can utilize a set of more than 200 SNPs that are found within haploblocks and can include analyzing a series of target chromosomal regions related to cancer or a chromosomal abnormality in a gestating fetus. Finally the method may use knowledge about chromosome crossover locations or a best fit algorithm for the analysis. The compositions may comprise more than 200 primers located within haplotype blocks known to show CNV.