The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 25, 2022
Filed:
Mar. 20, 2020
Applicants:
The Regents of the University of Colorado, Denver, CO (US);
Murdoch University, Murdoch, AU;
Inventors:
Marvin Caruthers, Boulder, CO (US);
Sibasish Paul, Boulder, CO (US);
Rakesh N. Veedu, Bull Creek, AU;
Katarzyna Jastrzebska, Boulder, CO (US);
Heera Krishna, Boulder, CO (US);
Assignee:
THE REGENTS OF THE UNIVERSITY OF COLORADO, Denver, CO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61P 21/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61P 21/00 (2018.01); C12N 2310/111 (2013.01); C12N 2310/314 (2013.01); C12N 2310/315 (2013.01); C12N 2310/321 (2013.01); C12N 2310/3233 (2013.01); C12N 2310/346 (2013.01); C12N 2310/3513 (2013.01); C12N 2310/3517 (2013.01); C12N 2320/33 (2013.01);
Abstract
Improved compositions and methods for treating a disease or disorder through target exon skipping, and preferably muscular dystrophy by administering antisense thiomorpholino molecules capable of binding to a selected target site in the human dystrophin gene to induce exon skipping to produce a functional Dystrophin protein.