The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 25, 2022

Filed:

Mar. 16, 2018
Applicants:

National University Corporation Chiba University, Chiba, JP;

Genedesign, Inc., Ibaraki, JP;

Nof Corporation, Tokyo, JP;

Inventors:

Hideo Iba, Chiba, JP;

Takeshi Haraguchi, Chiba, JP;

Hirokazu Nankai, Ibaraki, JP;

Hideaki Sato, Ibaraki, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12N 15/113 (2010.01); A61P 35/00 (2006.01); A61K 9/127 (2006.01); A61K 31/713 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 9/127 (2013.01); A61K 31/713 (2013.01); A61P 35/00 (2018.01); C12N 2310/113 (2013.01); C12N 2310/3231 (2013.01); C12N 2320/32 (2013.01);
Abstract

Provided is a novel technique for treating cancer using structurally-reinforced S-TuD. Provided are: a composition for the prevention or treatment of tumors, said composition comprising an miRNA inhibitory complex including RNA of analog thereof; and a method for preventing or treating tumors using said composition. The miRNA inhibitory complex preferably includes at least one double-stranded structure and an miRNA-binding sequence. Two strands of the miRNA binding sequence preferably bind individually to two strands on at least one end of the double-stranded structure. According to some of the aspects of the present invention, there is provided a delivery system for delivering such an miRNA inhibitory complex.


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