The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 25, 2022

Filed:

Aug. 27, 2019
Applicants:

Carnegie Mellon University, Pittsburgh, PA (US);

University of Connecticut, Farmington, CT (US);

Inventors:

Stefanie A. Sydlik, Pittsburgh, PA (US);

Anne M. Arnold, Pittsburgh, PA (US);

Brian D. Holt, Pittsburgh, PA (US);

Cato T. Laurencin, Avon, CT (US);

Leila Daneshmandi, Manchester, CT (US);

Stephen Schmidt, Pittsburgh, PA (US);

Assignees:

Carnegie Mellon University, Pittsburgh, PA (US);

University of Connecticut, Farmington, CT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08B 37/08 (2006.01); C08B 37/00 (2006.01); A61K 31/728 (2006.01); C08K 3/08 (2006.01); C08K 5/23 (2006.01); A61L 27/54 (2006.01); C08K 5/17 (2006.01);
U.S. Cl.
CPC ...
C08B 37/0072 (2013.01); A61K 31/728 (2013.01); A61L 27/54 (2013.01); C08B 37/0069 (2013.01); C08K 3/08 (2013.01); C08K 5/175 (2013.01); C08K 5/235 (2013.01); C08K 2003/0843 (2013.01); C08K 2003/0862 (2013.01);
Abstract

A compound includes a polysaccharide moiety and one or more chelating agents. The one or more chelating agents are covalently bonded to the polysaccharide moiety. The polysaccharide moiety can include a glycosaminoglycan moiety, such as a hyaluronic acid polymer or a sulfated glycosaminoglycan moiety. The compound can be used to treat or prevent a disease or disorder in a patient with a metal implant. The compound reduces a concentration of metal particulates or metal ions in the subject.


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