The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 25, 2022

Filed:

Feb. 02, 2022
Applicant:

Alpine Immune Sciences, Inc., Seattle, WA (US);

Inventors:

Ryan Swanson, Seattle, WA (US);

Michael Kornacker, Seattle, WA (US);

Assignee:

Alpine Immune Sciences, Inc., Seattle, WA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 14/705 (2006.01); A61K 47/65 (2017.01); A61K 47/68 (2017.01); A61K 47/64 (2017.01); C12N 15/62 (2006.01); A61P 35/00 (2006.01); A61K 38/17 (2006.01); A61K 35/768 (2015.01); C12N 15/85 (2006.01); A61P 37/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2827 (2013.01); A61K 35/768 (2013.01); A61K 47/64 (2017.08); A61K 47/65 (2017.08); A61K 47/68 (2017.08); C07K 14/70532 (2013.01); C12N 15/62 (2013.01); C12N 15/85 (2013.01); A61K 38/1774 (2013.01); A61P 35/00 (2018.01); A61P 37/00 (2018.01);
Abstract

Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.


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