The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 25, 2022
Filed:
Apr. 02, 2019
Applicant:
Ucb Biopharma Srl, Brussels, BE;
Inventors:
Teresa De Haro Garcia, Brussels, BE;
Lloyd Malcolm King, Slough, GB;
Martin Alexander Lowe, Slough, GB;
Malcolm Maccoss, Seabrook Island, SC;
Richard David Taylor, Slough, GB;
Zhaoning Zhu, Slough, GB;
Assignee:
Primary Examiner:
Int. Cl.
CPC ...
A61P 33/06 (2006.01); C07D 403/12 (2006.01); C07D 493/08 (2006.01); C07D 471/04 (2006.01); C07D 239/22 (2006.01); C07D 401/12 (2006.01); C07D 413/14 (2006.01); C07D 405/06 (2006.01); C07D 405/14 (2006.01); C07D 405/04 (2006.01);
U.S. Cl.
CPC ...
C07D 405/14 (2013.01); C07D 239/22 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 405/04 (2013.01); C07D 405/06 (2013.01); C07D 413/14 (2013.01); C07D 471/04 (2013.01); C07D 493/08 (2013.01);
Abstract
The application relates to a series of 2-imino-6-methylhexahydropyrimidin-4-one derivatives and 3-imino-5-methyl-1,2,4-thiadiazinane 1,1-dioxide derivatives of formula (I), substituted by an arylaminophenyl or heteroarylaminophenyl moiety. The compounds are potent inhibitors of the growth and propagation of theparasite in human blood and thus useful as pharmaceutical agents for the treatment of malaria.