The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 25, 2022
Filed:
Aug. 09, 2018
Applicants:
Brown University, Providence, RI (US);
Yale University, New Haven, CT (US);
Inventors:
Jack A. Elias, Providence, RI (US);
Chun Geun Lee, Woodbridge, CT (US);
Min-Jong Kang, Scarsdale, NY (US);
Assignees:
BROWN UNIVERSITY, Providence, RI (US);
YALE UNIVERSITY, New Haven, CT (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); A61K 48/00 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
A61K 38/177 (2013.01); G01N 33/6872 (2013.01); G01N 2800/122 (2013.01); G01N 2800/52 (2013.01);
Abstract
The methods and assays described herein relate to the diagnosis, prognosis, and treatment of subjects with emphysema, COPD, and/or cigarette-induced lung damage. In some embodiments, the methods and assays relate to subjects with a decreased level of NLRX1 expression. In some embodiments, the methods and assays relate to the administration of an agonist of NLRX1 and/or an inhibitor of MAVS.