The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 25, 2022

Filed:

Apr. 05, 2022
Applicant:

Applied Cognition, Inc., Los Altos Hills, CA (US);

Inventors:

Paul Dagum, Los Altos Hills, CA (US);

Gregory T. A. Kovacs, Palo Alto, CA (US);

Laurent B. Giovangrandi, Palo Alto, CA (US);

Carl J. Weber, Portola Valley, CA (US);

Joerg C. Student, San Francisco, CA (US);

Nathan Whipple, San Francisco, CA (US);

Jonathan I. Kaplan, Palo Alto, CA (US);

Assignee:

APPLIED COGNITION, INC., Los Altos Hills, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61B 5/372 (2021.01); A61B 5/0205 (2006.01);
U.S. Cl.
CPC ...
A61B 5/4088 (2013.01); A61B 5/0006 (2013.01); A61B 5/0205 (2013.01); A61B 5/372 (2021.01); A61B 5/418 (2013.01); A61B 5/6817 (2013.01); A61B 5/7275 (2013.01); A61B 2562/166 (2013.01);
Abstract

A computer-implemented method and system includes accessing neurophysiological and neurovascular data recorded during sleep. A function mapping is executed from said neurophysiological and neurovascular data to a target that is one of a glymphatic flow marker, a molecular analysis marker of neurodegeneration, or a neuroimaging marker of neurodegeneration. A target prediction model is output based on the function mapping. The target prediction model can receive new neurophysiological and neurovascular data and output a predicted marker of neurodegeneration.


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