The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 18, 2022
Filed:
Nov. 22, 2016
Applicant:
Massachusetts Institute of Technology, Cambridge, MA (US);
Inventors:
Michael S. Strano, Lexington, MA (US);
Gili H. Bisker Raviv, Cambridge, MA (US);
Assignee:
Massachusetts Institute of Technology, Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/543 (2006.01); B82Y 15/00 (2011.01); G01N 33/53 (2006.01); G01N 33/531 (2006.01); G01N 33/74 (2006.01);
U.S. Cl.
CPC ...
G01N 33/54346 (2013.01); B82Y 15/00 (2013.01); G01N 33/531 (2013.01); G01N 33/5308 (2013.01); G01N 33/74 (2013.01); G01N 2333/62 (2013.01);
Abstract
Corona Phase Molecular Recognition (CoPhMoRe) utilizing a heteropolymer adsorbed onto and templated by a nanoparticle surface to recognize a specific target analyte can be used for macromolecular analytes, including proteins. A variant of a CoPhMoRe screening procedure of single walled carbon nanotubes (SWCNT) can be used against a panel of human blood proteins, revealing a specific corona phase that recognizes fibrinogen and insulin, respectively, with high selectivity.