The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 18, 2022
Filed:
Jun. 26, 2019
Applicants:
University of Maryland, Baltimore County, Baltimore, MD (US);
National Institutes of Health, Bethesda, MD (US);
Inventors:
Songon An, Ellicott City, MD (US);
Danielle L. Schmitt, San Diego, CA (US);
James Inglese, Bethesda, MD (US);
Patricia Dranchak, Gaithersburg, MD (US);
Assignees:
UNIVERSITY OF MARYLAND, BALTIMORE COUNTY, Baltimore, MD (US);
NATIONAL INSTITUTES OF HEALTH, Bethesda, MD (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); G01N 21/64 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5035 (2013.01); C12N 15/85 (2013.01); C12Y 207/01011 (2013.01); G01N 21/6428 (2013.01); G01N 33/5011 (2013.01); G01N 2021/6439 (2013.01); G01N 2333/91215 (2013.01);
Abstract
A cell-based quantitative high-throughput screening assay to monitor the formation of PFK1-mEGFP clusters by the action of small molecules to identify small molecules that promote intracellular PFK1 clustering in a cell cycle-dependent manner and may be used to treat cancer.