The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 18, 2022

Filed:

Jan. 07, 2020
Applicant:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

Inventors:

Michael Marquant, Mannheim, DE;

Michael Reinhardt, Mannheim, DE;

Assignee:

ROCHE DIAGNOSTICS OPERATIONS, INC., Indianapolis, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/327 (2006.01); C12Q 1/00 (2006.01); G01N 33/487 (2006.01); G01N 33/49 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/006 (2013.01); G01N 27/3272 (2013.01); G01N 27/3274 (2013.01); G01N 33/48707 (2013.01); G01N 33/48721 (2013.01); G01N 33/49 (2013.01);
Abstract

A method of detecting at least one analyte in a test sample is provided comprising a) contacting the test sample (i) to an active chemistry matrix changing at least one electrochemical property dependent on an enzymatic activity active in the presence of the analyte, the active chemistry matrix contacting a first electrode; and (ii) to an inactive chemistry matrix, the inactive chemistry matrix contacting a second electrode, b) closing an electrical circuit including the first electrode, the second electrode, and the active chemistry matrix and inactive chemistry matrix, followed by determining a first value of the at least one electrochemical property, c) inverting electrical polarity of the electrical circuit of b), followed by determining a second value of the at least one electrochemical property, and d) detecting the at least one analyte based on the first value and on the second value.


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