The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 18, 2022
Filed:
Dec. 04, 2015
Massachusetts Institute of Technology, Cambridge, MA (US);
Trustees of Boston University, Boston, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Russell-John Krom, Boston, MA (US);
James J. Collins, Newton, MA (US);
Prerna Saluja Bhargava, Watertown, MA (US);
Michael Andrew Lobritz, Newton, MA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
Trustees of Boston University, Boston, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Abstract
Provided herein, in some embodiments, are engineered phagemids that comprise at least one synthetic genetic circuit, wherein the at least one synthetic genetic circuit comprises gene sequences encoding at least one non-lytic antimicrobial peptides (AMPs) and/or antibacterial toxin proteins, a stable origin of replication, and a bacteriophage-packaging signal, wherein the engineered phagemid does not comprise some or all gene sequences encoding bacteriophage proteins required for assembly of a bacteriophage particle.