The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 18, 2022
Filed:
Jun. 16, 2016
Applicant:
Poseida Therapeutics, Inc., San Diego, CA (US);
Inventors:
Eric Ostertag, San Diego, CA (US);
Tseten Yeshi, San Diego, CA (US);
Xianghong Li, San Diego, CA (US);
Assignee:
Poseida Therapeutics, Inc., San Diego, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 9/22 (2006.01); C12N 9/16 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/11 (2013.01); C12N 9/16 (2013.01); C12N 9/22 (2013.01); A61K 48/00 (2013.01); C07K 2319/80 (2013.01); C12N 2310/20 (2017.05);
Abstract
Disclosed are compositions and methods for directing proteins to specific loci in the genome and uses thereof. In one aspect, the disclosed methods allow for directing proteins to specific loci in the genome of an organism, including the steps of providing a fusion protein comprising a DNA localization component and an effector molecule. Preferred embodiments of the disclosure include, but are not limited to, the following fusion proteins: dSaCas9-Clo051, dCas9-Clo051,-TALE-Clo051, and-TALE-Clo051.