The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 18, 2022
Filed:
Oct. 28, 2016
Biocore Co., Ltd., Seoul, KR;
Seung Yong Hwang, Seoul, KR;
Moon Ju Oh, Seoul, KR;
Seung Jun Kim, Gyeonggi-do, KR;
Jong Pil Youn, Gyeonggi-do, KR;
Ji Hoon Kim, Gyeonggi-do, KR;
Seung Yong Lee, Gyeonggi-do, KR;
Jeong Jin Ahn, Seoul, KR;
Joon Soo Park, Seoul, KR;
Hyo Jung Choi, Gyeonggi-do, KR;
BIOCORE CO., LTD., Seoul, KR;
Abstract
The present invention relates to a method for prenatal diagnosis using digital PCR, and more particularly to a method for providing information for diagnosis of chromosomal aneuploidy in a fetus, comprising: (a) extracting DNAs from pregnant woman's blood; (b) classifying the DNAs according to size to obtain DNAs having a size of 1,000 bp or less; (c) performing digital PCR using the obtained DNAs of step (b), for a control gene located on a chromosome not associated with chromosomal aneuploidy and a target gene located on a chromosome associated with chromosomal aneuploidy; (d) calculating a ratio of a quantitative digital PCR value of the target gene to a quantitative digital PCR value of the control gene; and (e) determining that when the ratio calculated in step (d) is 0.70-1.14, a chromosome number of the fetus is normal.