The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 18, 2022
Filed:
Oct. 25, 2021
Xenotherapeutics, Inc., Boston, MA (US);
Xenotherapeutics Corporation, Enfield, NH (US);
Paul W. Holzer, Enfield, NH (US);
Jon Adkins, Londonderry, NH (US);
Rodney L. Monroy, North Fort Myers, FL (US);
Elizabeth J. Chang, Pittsford, NY (US);
XenoTherapeutics, Inc., Boston, MA (US);
Alexis Bio, Inc., Grantham, NH (US);
Abstract
A biological system for generating and preserving a repository of personalized, humanized transplantable cells, tissues, and organs for transplantation, wherein the biological system is biologically active and metabolically active, the biological system having genetically reprogrammed cells, tissues, and organs in a non-human animal for transplantation into a human recipient, wherein the non-human animal does not present one or more surface glycan epitopes and specific sequences from the wild-type swine's SLA is replaced with a synthetic nucleotides based on a human captured reference sequence from a human recipient's HLA.