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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11473054 B1

PDFFull Text
Date of Patent:
Oct. 18, 2022

Filed:

Jan. 31, 2017

Method of producing three-dimensional tissue having vascular system structure, and three-dimensional tissue including gel having vascular system structure

Applicant:

Osaka University, Suita, JP;

Inventor:

Michiya Matsusaki, Suita, JP;

Assignee:

OSAKA UNIVERSITY, Suita, JP;

Attorney:

Oblon, McClelland, Maier & Neustadt, L.L.P.

Primary Examiner:

Evelyn Y Pyla

Int. Cl.
CPC ...
C12N 5/00 (2006.01); A61L 27/22 (2006.01); A61L 27/38 (2006.01); A61L 27/50 (2006.01); C12N 5/077 (2010.01); C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0062 (2013.01); A61L 27/222 (2013.01); A61L 27/3826 (2013.01); A61L 27/507 (2013.01); C12N 5/00 (2013.01); C12N 5/069 (2013.01); C12N 5/0652 (2013.01); A61F 2240/002 (2013.01); A61L 2430/34 (2013.01);
Abstract

Provided is a method for producing a three-dimensional tissue having a vascular system structure, said method comprising: (a) a step for forming a vascular system structure template using a gel; (b) a step for forming a three-dimensional tissue in the vicinity of the template; (c) a step for dissolving the template using a cationic solution; and (d) a step for seeding vascular endothelial cells and/or lymphatic vessel endothelial cells in a void remaining after the dissolution of the template. Also provided is a method for producing a three-dimensional tissue having a vascular system structure, said method comprising: (i) a step for forming a vascular system structure template using a gel; (ii) a step for seeding vascular endothelial cells and/or lymphatic vessel endothelial cells on the template; (iii) a step for forming a three-dimensional tissue in the vicinity of the cells seeded above; and (iv) a step for dissolving the template using a cationic solution. Also provided is a three-dimensional tissue comprising a gel which has a vascular system structure.

Find Patent Forward Citations

Matsusaki, Michiya. (2022). Method of producing three-dimensional tissue having vascular system structure, and three-dimensional tissue including gel having vascular system structure (U.S. Patent No. 11473054). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11473054

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