The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 18, 2022
Filed:
Feb. 17, 2021
Applicant:
Purdue Research Foundation, West Lafayette, IN (US);
Inventors:
Elizabeth M. Murphy Topp, Lafayette, IN (US);
Hamed Tabatabaei Ghomi, San Diego, CA (US);
Markus Lill, West Lafayette, IN (US);
Shenbaga Moorthy Balakrishnan, Virudhunagar District, IN;
Assignee:
Purdue Research Foundation, West Lafayette, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/26 (2006.01); A61K 47/52 (2017.01); C07K 14/605 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/605 (2013.01); A61K 38/26 (2013.01); A61K 47/52 (2017.08); A61K 38/00 (2013.01);
Abstract
The invention generally relates to modified glucagon molecules. In certain embodiments, the invention provides a glucagon molecule that includes one or more modified amino acids to result in the glucagon molecule being soluble at a substantially neutral pH and resistant to fibrillation. Modifications may include, for example, phosphorylation or sulfation.