The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 18, 2022
Filed:
Jun. 13, 2017
Applicant:
Torque Therapeutics, Inc., Cambridge, MA (US);
Inventors:
Ferdinando Pucci, Quincy, MA (US);
Thomas Lars Andresen, Vanlose, DK;
Douglas Scott Jones, Newton, MA (US);
Ulrik Nielsen, Quincy, MA (US);
James Andrew Rakestraw, Somerville, MA (US);
Assignee:
Torque Therapeutics, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/20 (2006.01); A61K 38/17 (2006.01); A61K 47/54 (2017.01); A61K 47/68 (2017.01); C07K 14/54 (2006.01); A61K 47/69 (2017.01); C07K 14/56 (2006.01); C07K 14/565 (2006.01); C07K 14/73 (2006.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
C07K 14/54 (2013.01); A61K 47/68 (2017.08); A61K 47/6901 (2017.08); C07K 14/56 (2013.01); C07K 14/565 (2013.01); C07K 14/70514 (2013.01); C07K 14/70517 (2013.01); C07K 14/70553 (2013.01); C07K 14/70589 (2013.01); C07K 2317/52 (2013.01); C07K 2319/30 (2013.01);
Abstract
The present disclosure features, at least in part, methods for conserving cell function, e.g., immune cell function, e.g., after one or more cycles of freezing and/or thawing the nucleated cell. In embodiments, the methods comprise contacting an immune cell with a protein nanoparticle comprising an IL-15 complex.