The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 18, 2022
Filed:
Sep. 19, 2018
Applicant:
Biocon Biologics India Limited, Bengaluru, IN;
Inventors:
Sai Srikar Kandukuri, Guntur, IN;
Vibhava Shukla, Bengaluru, IN;
Arul Marimuthu, Thanjavur, IN;
Mukul Pathy, Bhubaneswar, IN;
Partha P. Hazra, Bengaluru, IN;
Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B01D 9/02 (2006.01); C07K 14/62 (2006.01); F26B 5/14 (2006.01); C07K 1/30 (2006.01); C07K 1/34 (2006.01); B01D 9/00 (2006.01);
U.S. Cl.
CPC ...
C07K 1/306 (2013.01); C07K 1/34 (2013.01); C07K 14/62 (2013.01); F26B 5/14 (2013.01); B01D 2009/009 (2013.01);
Abstract
The present invention describes the integration of preparative crystallization, crystal separation, crystal washing and freeze-drying processes of insulin and insulin analogues into single continuous process using pressure filtration. The process facilitates time reduction and outlines the novel design of using multiple organic solvent washes and nitrogen gas purging for the removal of imbibed water and achieve final drug substance that meets the quality specifications.