The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 18, 2022

Filed:

Aug. 23, 2018
Applicant:

Cell2in, Inc., Seoul, KR;

Inventors:

Heun Soo Kang, Seoul, KR;

Hye Mi Kim, Seoul, KR;

Ji Eun Song, Seoul, KR;

Myoung Jin Kim, Seoul, KR;

Ki Hang Choi, Seoul, KR;

Assignee:

CELL2IN, INC., Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 9/6561 (2006.01); C07D 491/147 (2006.01); G01N 21/64 (2006.01); G01N 33/483 (2006.01); G01N 33/52 (2006.01);
U.S. Cl.
CPC ...
C07F 9/6561 (2013.01); C07D 491/147 (2013.01); G01N 21/64 (2013.01); G01N 33/483 (2013.01); G01N 33/52 (2013.01);
Abstract

The present invention relates to a real-time fluorescence imaging sensor for measuring glutathione in cell organelles and a method for fabricating the same. More specifically, the present invention relates to a novel compound for measuring glutathione in cell organelles, a method for preparing the novel compound, a real-time fluorescence imaging sensor for measuring glutathione in cell organelles, which comprises the novel compound, a method for fabricating the imaging sensor, and a method of measuring glutathione in cell organelles by use of the imaging sensor. When the composition comprising the compound according to the present invention is used, it can measure the antioxidant activity of the organelle mitochondria or Golgi apparatus in living cells, particularly stem cells, and can screen highly active stem cells based on the results obtained by measuring the antioxidant activity of the cell organelle.


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