The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 18, 2022
Filed:
Dec. 04, 2020
Astrazeneca Ab, Sodertalje, SE;
Alexander Hird, Waltham, MA (US);
Matthew Belmonte, Waltham, MA (US);
Wenzhan Yang, Waltham, MA (US);
Paul Secrist, Waltham, MA (US);
Daniel Robbins, Waltham, MA (US);
Steven Kazmirski, Waltham, MA (US);
Dedong Wu, Waltham, MA (US);
Bo Peng, Waltham, MA (US);
Jeffrey Johannes, Waltham, MA (US);
Michelle Lamb, Waltham, MA (US);
Qing Ye, Waltham, MA (US);
Xiaolan Zheng, Waltham, MA (US);
AstraZeneca AB, Sodertalje, SE;
Abstract
Disclosed is a compound which is 17-chloro-5,13,14,22-tetramethyl-28-oxa-2,9-dithia-5,6,12,13,22-pentaazaheptacyclo[27.7.1.10000]octatriaconta-1(37),4(38),6,11,14,16,18,20,23,29,31,33,35-tridecaene-23-carboxylic acid (Formula I) and enantiomers and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions of 17-chloro-5,13,14,22-tetramethyl-28-oxa-2,9-dithia-5,6,12,13,22-pentaazaheptacyclo[27.7.1.10000]octatriaconta-1(37),4(38),6,11,14,16,18,20,23,29,31,33,35-tridecaene-23-carboxylic acid, and enantiomers and pharmaceutically acceptable salts thereof, and methods of treating cancer with such compounds and compositions.