The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 18, 2022

Filed:

Jan. 18, 2019
Applicant:

Array Biopharma Inc., Boulder, CO (US);

Inventors:

Shane M. Walls, Boulder, CO (US);

Li Ren, Boulder, CO (US);

Ginelle A. Ramann, Boulder, CO (US);

David A. Moreno, Boulder, CO (US);

Andrew T. Metcalf, Boulder, CO (US);

Elizabeth A. McFaddin, Boulder, CO (US);

Gabrielle R. Kolakowski, Longmont, CO (US);

James F. Blake, Boulder, CO (US);

Donghua Dai, Boulder, CO (US);

Julia Haas, Boulder, CO (US);

Yutong Jiang, Boulder, CO (US);

Dean Kahn, Boulder, CO (US);

Assignee:

Array BioPharma Inc., Boulder, CO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61P 35/00 (2006.01); C07F 9/6561 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61P 35/00 (2018.01); C07F 9/6561 (2013.01);
Abstract

Provided herein are compounds of the Formula I: and tautomers and pharmaceutically acceptable salts and solvates thereof, wherein R, Rand Rhave the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders.


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