The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 18, 2022

Filed:

Mar. 29, 2018
Applicants:

The George Washington University, a Congressionally Chartered Not-for-profit Corporation, Washington, DC (US);

The Board of Trustees of the University of Illinois, Urbana, IL (US);

Inventors:

Alejandro Villagra, Falls Church, VA (US);

Alan P. Kozikowski, Chicago, IL (US);

Sida Shen, Chicago, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 261/18 (2006.01); C07D 413/06 (2006.01); C07D 417/06 (2006.01); C07D 471/04 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 261/18 (2013.01); A61P 35/00 (2018.01); C07D 413/06 (2013.01); C07D 417/06 (2013.01); C07D 471/04 (2013.01); A61K 45/06 (2013.01);
Abstract

The present disclosure provides compounds represented by Formula (I): and pharmaceutically acceptable salts, solvates, e.g., hydrates, and prodrugs thereof wherein X and n are as defined as set forth in the specification. The present disclosure also provides compounds of Formula (I) for use to treat diseases and conditions, e.g., cancer, wherein inhibition of HDAC provides a benefit.


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