The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 18, 2022

Filed:

Dec. 18, 2017
Applicant:

Oligomerix Inc., Bronx, NY (US);

Inventors:

Eliot J. Davidowitz, West Hempstead, NY (US);

James G. Moe, Stamford, CT (US);

Allen B. Reitz, Lansdale, PA (US);

Haiyan Bian, Princeton, NJ (US);

Charles Gluchowski, Danville, CA (US);

James Hendrix, Wilmington, MA (US);

Albert S. Yehaskel, Great Neck, NY (US);

Mark E. McDonnell, Lansdale, PA (US);

H. Marie Loughran, Perkasie, PA (US);

Assignee:

Oligomerix, Inc., White Plains, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/04 (2006.01); C07D 239/91 (2006.01); C07D 401/14 (2006.01); C07D 471/04 (2006.01); C07D 495/04 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 239/91 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 471/04 (2013.01); C07D 495/04 (2013.01); A61K 45/06 (2013.01);
Abstract

Novel quinazolinones useful as inhibitors of tau oligomer formation, useful for the treatment of neurodegenerative diseases and related conditions are disclosed. The invention also relates to the pharmaceutically acceptable salts of said compounds, processes for the preparation of said compounds, intermediates used in the preparation of said compounds, and pharmaceutical compositions containing said compounds. The invention further relates to methods of use of said compounds, salts of said compounds, and said compositions in treating neurodegenerative diseases and related conditions.


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