The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 18, 2022
Filed:
Apr. 04, 2018
Novo Nordisk A/s, Bagsvaerd, DK;
Tina Moeller Tagmose, Ballerup, DK;
Peter Madsen, Bagsvaerd, DK;
Thomas Boerglum Kjeldsen, Virum, DK;
Lone Pridal, Greve, DK;
Leonardo De Maria, Partille, SE;
Zhaosheng Lin, Markham, CA;
Zhe Wan, Beijing, CN;
Yuanyuan Zhang, Beijing, CN;
Lennart Lykke, Copenhagen, DK;
Martin Werner Borchsenius Muenzel, Broenshoej, DK;
Janos Tibor Kodra, Koebenhavn, DK;
Novo Nordisk A/S, Bagsvaerd, DK;
Abstract
This invention is in the field of protein conjugates. More specifically the invention relates to oligomer extended insulins with covalently attached Fc monomer polypeptides, for use in the treatment of a metabolic disorder or condition, and to methods of producing such oligomer extended insulin-Fc conjugates. The invention also relates to novel Fc fragments, to intermediate products, and to the use of such intermediate products in processes for the synthesis of the oligomer extended insulin-Fc conjugates of the invention. Finally the invention provides pharmaceutical compositions comprising the oligomer extended insulin-Fc conjugates of the invention, and relates to the use of such compositions for the treatment or prevention of medical conditions relating to metabolic disorders or conditions.