The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 18, 2022
Filed:
Oct. 10, 2019
The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);
Regents of the University of Minnesota, Minneapolis, MN (US);
Jonathan Serody, Chapel Hill, NC (US);
James Coghill, Chapel Hill, NC (US);
Danny Bruce, Chapel Hill, NC (US);
Bruce Blazar, Golden Valley, MN (US);
Heather Stefanski, Minneapolis, MN (US);
Benjamin Vincent, Chapel Hill, NC (US);
The University of North Carolina at Chapel Hill, Chapel Hill, NC (US);
Regents of the University of Minnesota, Minneapolis, MN (US);
Abstract
ILC2 cells play a role in the pathogenesis of graft versus host disease (GvHD) and idiopathic pneumonia syndrome (IPS), both conditions associated with allogeneic stem cell transplantation. Infusion of IL-33 activated ILC2 cells into patients with ongoing GvHD or IPS, or prior to onset of GvHD or IPS in susceptible patients, substantially ameliorates the disease and improves survival.