The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 18, 2022
Filed:
Dec. 03, 2015
Applicants:
Celgene Corporation, Summit, NJ (US);
Acceleron Pharma Inc., Cambridge, MA (US);
Inventors:
Kenneth M. Attie, Boston, MA (US);
Christopher Rovaldi, Swampscott, MA (US);
Abderrahmane Laadem, Belle Mead, NJ (US);
Assignees:
CELGENE CORPORATION, Summit, NJ (US);
ACCELERON PHARMA INC., Cambridge, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 39/00 (2006.01); C07K 14/00 (2006.01); C07K 16/00 (2006.01); G01N 33/50 (2006.01); A61K 38/17 (2006.01); C07K 14/71 (2006.01); G01N 33/49 (2006.01);
U.S. Cl.
CPC ...
A61K 38/179 (2013.01); C07K 14/71 (2013.01); G01N 33/49 (2013.01); C07K 2319/30 (2013.01);
Abstract
Provided herein are methods for the treatment in a subject of anemia, anemia requiring RBC transfusion, low or intermediate-1-risk myelodysplastic syndromes (MDS), and/or non-proliferative chronic myelomonocytic leukemia (CMML) in any mammals wherein the methods comprise administration of Activin-ActRII signaling inhibitors to a subject in need of the treatment.