The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 18, 2022
Filed:
Apr. 09, 2019
Applicant:
The Board of Regents of the University of Texas System, Austin, TX (US);
Inventors:
Eric Olson, Dallas, TX (US);
Douglas P. Millay, Frisco, TX (US);
Assignee:
The Board of Regents of The University of Texas System, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/17 (2006.01); A61K 45/06 (2006.01); C07K 14/47 (2006.01); A61K 9/00 (2006.01); C12N 5/16 (2006.01); C12N 15/02 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1719 (2013.01); A61K 9/0019 (2013.01); A61K 45/06 (2013.01); C07K 14/4716 (2013.01); C12N 5/16 (2013.01); C12N 15/02 (2013.01); C12N 2740/10043 (2013.01); C12N 2740/10071 (2013.01);
Abstract
The present disclosure describes the fusogenic activity of the Myomaker protein. This polypeptide, when expressed in non-muscle cells, is able to drive fusion of the cell with a muscle cell, but not with other non-muscle cells. The use of this protein and cell expressing it in the delivery of exogenous genetic material to muscle cells also is described.